Welcome to Nanba, the world's largest and most impenetrable prison. Locked away in Cell Block 13 are four inmates - pill-popping Nico, burly food-loving Rock, gambling charmer Uno and Jyugo, who was born at Nanba and has made more escapes than any other prisoner there - who provide more than enough trouble for the tough Officer Hajime. Follow them and their numerous adventures within the walls of Nanba.

Kagami Junichirou was known as a physics genius when he was a teenager, and he was even published in "Nature." However, after college, he suddenly lost all interest in science. As a NEET, he's devoted himself to his anime blog and nerdy collecting habits. He claims he has a serious illness called "I can't do anything I don't want to do." Desperate to get him to do something with his life, his little sister manages to get him a job teaching physics at his old high school. He's certainly an unconventional teacher, but he becomes fairly popular with the students. After helping a girl who's being ruthlessly bullied, Kagami finds that he actually likes teaching. Will he continue his career as a weird teacher? Will he go back into physics? Or will he end up back where he started?